hemoglobin variants and their clinical significance

Hemoglobin variants refer to genetic mutations that cause alterations in the structure or function of hemoglobin, the protein that carries oxygen in red blood cells. These variations can lead to different types of hemoglobin with distinct characteristics. The clinical significance of hemoglobin variants lies in their potential to affect the individual's health. Some variants, such as sickle cell disease or thalassemia, can cause serious health problems, including anemia or organ damage. Other variants may be less severe and have milder or no noticeable effects. Understanding these variants is crucial for accurate diagnosis and appropriate medical management.

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